Top Blockchain Startups in the USA You Need to Know About Now
Blockchain technology is revolutionizing industries across the United States, from finance to supply chain management, and startups are at the forefront of this transformation. As of March 18, 2025, the blockchain market is booming, with innovative companies leveraging decentralized systems to solve real-world problems. Here’s a look at some of the most exciting blockchain startups in the USA that are shaping the future.
1. Spectral Finance
Founded in 2020, Spectral Finance is a fintech startup making waves in decentralized finance (DeFi). Based in the USA, it has developed a liquidity aggregation platform that uses blockchain to calculate on-chain credit scores, improving credit risk evaluation. Its novel collateral subsidization model is designed to empower users by identifying optimal DeFi protocols for programmable credit solutions. This startup is a prime example of how blockchain can decentralize traditional financial systems.
2. Coinbase
No list of blockchain startups is complete without Coinbase, headquartered in San Francisco. Launched in 2012, Coinbase has grown into one of the world’s largest cryptocurrency exchanges, serving nearly 100 million users globally. Beyond trading, it offers a mobile wallet and secure storage, making crypto accessible to the masses. Its longevity and scale highlight its pivotal role in driving blockchain adoption in the USA.
3. Fireblocks
Fireblocks, based in New York, is a blockchain security powerhouse founded in 2018. It provides institutional-grade solutions for custody, treasury management, and decentralized finance access. With over $2 trillion in secured crypto assets for more than 1,000 clients, Fireblocks demonstrates how blockchain can enhance security and efficiency for businesses. Its rapid growth underscores its importance in the ecosystem.
4. Chainlink Labs
Chainlink Labs, also based in San Francisco, is transforming how blockchains interact with real-world data. Founded in 2017, it offers a Web3 services platform that connects smart contracts to external data sources, enabling interoperability between public and private blockchains. Partnerships with giants like Amazon Web Services and Google Cloud showcase its influence in bridging traditional tech with blockchain innovation.
5. Blockdaemon
Blockdaemon, established in 2017 and headquartered in Los Angeles, simplifies blockchain infrastructure for businesses. Supporting over 60 blockchain networks, it provides node management tools that allow companies to deploy and manage decentralized applications effortlessly. Its focus on scalability and ease of use makes it a go-to for enterprises entering the blockchain space.
Why These Startups Matter
The blockchain industry in the USA is projected to reach a market size of $67.4 billion by 2026, according to a report by MarketsandMarkets. These startups are not just riding the wave—they’re driving it. From enhancing financial inclusion to securing digital assets, they’re tackling challenges that traditional systems can’t address. The USA’s robust tech ecosystem, coupled with increasing investment in blockchain—over 90% of U.S. banks are exploring the technology, per a study by Accenture—creates a fertile ground for these companies to thrive.
Emerging Trends
Recent trends show blockchain startups focusing on interoperability, security, and real-world applications. For instance, Spectral Finance’s credit scoring innovation hints at a future where DeFi replaces outdated financial models. Meanwhile, Chainlink’s efforts in connecting blockchains to external data could unlock new use cases in industries like healthcare and logistics.
Sources
- Information on Spectral Finance sourced from F6S (f6s.com).
- Coinbase data derived from Crunchbase (crunchbase.com) and its official site.
- Fireblocks details from Exploding Topics (explodingtopics.com).
- Chainlink Labs insights from Built In (builtin.com).
- Blockdaemon information from its official site and Exploding Topics.
- Market size projection from MarketsandMarkets; banking stat from Accenture.
